Part:BBa_K5091008
pmsC
The pmsC gene from Pseudomonas fluorescens A506 encodes isochorismate synthase (ICS), an enzyme involved in the biosynthesis of salicylic acid (SA). This gene plays a critical role in the first step of the two-enzyme pathway that converts chorismate to salicylic acid, a key signaling molecule in plant defense. Isochorismate synthase catalyzes the conversion of chorismate into isochorismate, which is then further processed by isochorismate pyruvate lyase (encoded by pmsB) to produce salicylic acid.
Salicylic acid is an important compound in plant-microbe interactions, known for inducing systemic acquired resistance (SAR) in plants and enhancing their immune response against various pathogens. The production of SA by Pseudomonas fluorescens A506 makes this gene valuable for projects focused on biological control or improving plant immunity. PmsC, when expressed in combination with pmsB, can be used to biosynthesize salicylic acid in microbial systems or engineered organisms.
Sequence and Features
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 112
Illegal PstI site found at 493
Illegal PstI site found at 871 - 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 112
Illegal PstI site found at 493
Illegal PstI site found at 871 - 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 654
Illegal BamHI site found at 852 - 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 112
Illegal PstI site found at 493
Illegal PstI site found at 871 - 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 112
Illegal PstI site found at 493
Illegal PstI site found at 871 - 1000COMPATIBLE WITH RFC[1000]
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